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Increased deaths shadow AstraZeneca, Daiichi's Enhertu first-line lung cancer data

Published

13 September 2026

Topic

opportunities

Sectors

Biotech

Geography

United States

Source

Read at fiercepharma.com

Verified

Fusion42 · 13 September 2026 · Fusion42 review

A phase 3 trial shows AstraZeneca and Daiichi Sankyo's Enhertu increased progression-free survival in HER2-mutant non-small cell lung cancer but revealed a 15% higher risk of death compared to standard treatment, complicating potential FDA approval.

This Wire brief sits within Fusion42's coverage of Biotech.

◆ The Wire takeaway

You face tougher FDA scrutiny for HER2-targeted lung cancer drugs due to survival risks seen with Enhertu. Accelerate safety monitoring improvements or adjust trial designs now to sustain market entry chances.

Coverage

1 source · 13 Sep 2026

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Topics

Biotechlung-canceroncologydrug-safetyFDA-approvalclinical-trials