FDA Issues Proposed Rule on Substances Generally Recognized as Safe (GRAS)

FDA proposed a rule requiring mandatory notification for substances self-determined as GRAS in human or animal food, shifting from a voluntary to a mandatory framework while maintaining no pre-market approval. The rule includes exceptions, a streamlined submission for substances already in commerce, and aims to improve transparency and enforcement prioritisation.

This Wire brief sits within Fusion42's coverage of Foodtech. Wire is Fusion42's founder-focused intelligence feed: each story is connected to the funds and startups it names — every one with a live profile on Raise or Scout — so founders can follow the capital and the momentum behind the headline rather than just the headline itself. Wire analysis is one of the live surfaces Arthur reasons over.