No More GRAS Self-Affirmations? FDA Proposes Mandatory GRAS Notifications

The FDA proposes for the first time to require mandatory notifications for all substances marketed in food or animal feed under GRAS status, eliminating the option for self-affirmation without agency notification. This policy shift aims to increase transparency and FDA oversight on substances entering the food supply, impacting manufacturers, suppliers, and importers across the United States.

This Wire brief sits within Fusion42's coverage of Foodtech, and 5 sources have reported it between 11 Aug 2026 and 19 Aug 2026.