Wire · opportunities
RiboX Secures FDA IND Clearance for World's First Circular RNA-Based In Vivo CAR-T Therapy
◆ Sectors
Biotech
◆ Geography
United States
◆ Source
◆ Verified
Fusion42 · 6 September 2026 · Fusion42 review
RiboX received FDA IND clearance to begin Phase I clinical trials for RXIM002, the first circular RNA-based in vivo CAR-T therapy targeting autoimmune cytopenias using a targeted lipid nanoparticle delivery platform.
This Wire brief sits within Fusion42's coverage of Biotech.
◆ ◆ The Wire takeaway
You must now see FDA clearance of circular RNA-based therapies as a real clinical gateway. This opens the door for RNA therapeutic founders to move fast on in vivo CAR-T candidates with improved patient accessibility.
◆ Coverage
1 source · 6 Sep 2026
◆ Related on Wire
◆ Topics
Biotechcar-t-therapycircular-rnafda-indautoimmune-diseaserna-therapeutics