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Rapid Whole-Genome Sequencing Is Leaving the Research Ward and Entering the PICU Protocol
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Fusion42 · 25 August 2026 · Fusion42 review
Rapid whole-genome sequencing (rWGS) has transitioned from a research tool to a citywide clinical standard across multiple pediatric ICUs, delivering diagnoses in a mean of 3.4 days, challenging existing regulatory frameworks and clinical trial protocols in neonatal and pediatric rare disease drug development.
This Wire brief sits within Fusion42's coverage of Health.
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You must update trial protocols immediately to reflect that hospitals like Seattle Children's treat rapid whole-genome sequencing results as routine diagnostics, not investigational data. Your eligibility criteria and timelines are obsolete, risking enrolment delays and compromised randomization.
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1 source · 25 Aug 2026
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