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United Therapeutics Corporation Announces ADVANCE OUTCOMES Study of Ralinepag ...
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Fusion42 · 29 July 2026 · Fusion42 review
United Therapeutics announced its phase 3 study for ralinepag, a once-daily oral drug for pulmonary arterial hypertension (PAH), met its primary endpoint, reducing clinical worsening events by 55% versus placebo. The results, published in The Lancet, support the company's New Drug Application submitted to the FDA.
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◆ ◆ The Wire takeaway
The clinical benchmark for new pulmonary arterial hypertension drugs just got higher. If you are developing a competitor, you now need to prove your treatment works on top of a potent oral drug, not just older therapies.
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