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We Might Have Been Wrong About How the Immune System Ages

Published

8 September 2026

Topic

opportunities

Sectors

Longevity & WellnessBiotech

Source

Read at medscape.com

Verified

Fusion42 · 8 September 2026 · Fusion42 review

New research shows that the immune system may not simply decline with age but instead adapts by expanding rare CD4 cytotoxic T lymphocytes, especially in supercentenarians, which might help them survive longer by targeting persistent threats and senescent cells.

This Wire brief sits within Fusion42's coverage of Longevity & Wellness and Biotech.

◆ The Wire takeaway

Founders in longevity must now build on the idea that immune ageing could be an adaptive process, unlocking new paths for therapies that enhance immune cell function in the very old. Your models and product roadmaps need updating to focus on boosting immune resilience, not just slowing decline.

Coverage

1 source · 8 Sep 2026

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Topics

Longevity & WellnessBiotechimmune-systemaginglongevitycd4-ctlsenescence