Five labs fail to replicate therapeutic effects of psilocybin in mice

Five different research labs conducted a joint study using identical protocols and found that psilocybin failed to produce replicable long-lasting therapeutic effects on anxiety or depression in mice, though it did reduce fear expression and increase acute anxiety. This raises questions about the reliability of preclinical animal behavior experiments underpinning psychedelic therapeutic claims.

This Wire brief sits within Fusion42's coverage of Biotech.