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Novo, Orbis sign up to $1.4 billion deal to develop oral drugs

Published

17 September 2026

Topic

opportunities

◆ Sectors

Biotech

◆ Geography

United States

◆ Source

Read at wtvbam.com →

◆ Verified

Fusion42 · 17 September 2026 · Fusion42 review

Orbis Medicines and Novo Nordisk have signed a drug discovery and licensing deal worth up to $1.4 billion to develop oral therapies for cardiometabolic diseases using Orbis' AI-enabled platform for macrocycle drug discovery. Novo will also make a strategic investment in Orbis, aiming to transform treatments traditionally administered via injections into oral forms.

This Wire brief sits within Fusion42's coverage of Biotech, and 2 sources have reported it.

◆ ◆ The Wire takeaway

You need to recognise the jump in AI-driven drug discovery turning injectables into oral medicines. Investors and developers in biotech should prepare for rising competition and partnership opportunities in macrocycle therapeutics now backed by major pharma.

◆ Coverage

2 sources · 17 Sep 2026

◆ Related on Wire

◆ Topics

Biotechoral-drugscardiometabolicmacrocyclesAI-drug-discoverypharma-collaboration