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COPD trial wins spur broad respiratory hopes

Published

5 October 2026

Topic

opportunities

◆ Sectors

Biotech

◆ Geography

United States

◆ Source

Read at nature.com →

◆ Verified

Fusion42 · 5 October 2026 · Fusion42 review

AstraZeneca's IL-33-targeted antibody tozorakimab has shown a 30% reduction in COPD exacerbations across all blood eosinophil counts, addressing a major treatment gap. The company has filed for FDA approval, expecting a decision in early 2027, and this success could trigger broader development of IL-33-targeted therapies in respiratory diseases.

This Wire brief sits within Fusion42's coverage of Biotech.

◆ ◆ The Wire takeaway

Your respiratory biotech project can now target a proven market gap in COPD beyond eosinophilic patients. Tozorakimab's pending US approval opens a path to compete in biologics that treat hard-to-control lung inflammation.

◆ Coverage

1 source · 5 Oct 2026

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Biotechcopdbiologicsil-33asthmarespiratory-diseaseregulatory-approval