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Wire · operational-macro

Actimed Completes Enrollment in PROACT Trial of S-Pindolol With Semaglutide

Published

24 September 2026

Topic

operational-macro

◆ Sectors

Longevity & WellnessBiotechDrug Discovery

◆ Geography

United States

◆ Source

Read at clinicaltrialvanguard.com →

◆ Verified

Fusion42 · 24 September 2026 · Fusion42 review

Actimed Therapeutics has completed patient enrollment in the PROACT Phase 2a trial testing S-pindolol benzoate alongside and after semaglutide therapy to address muscle loss during weight management. The trial targets the unmet need of preserving lean mass while using GLP-1 drugs, with results expected to influence obesity treatment strategies.

This Wire brief sits within Fusion42's coverage of Longevity & Wellness, Biotech and Drug Discovery.

◆ ◆ The Wire takeaway

You have a rare chance to tackle the biggest gap in GLP-1 weight loss: muscle loss during and after treatment. Actimed’s trial opening signals a new adjunct drug opportunity for obesity therapies that protect lean mass and improve patient long-term outcomes.

◆ Coverage

1 source · 24 Sep 2026

◆ Related on Wire

◆ Topics

Longevity & WellnessBiotechDrug Discoveryobesity-treatmentmuscle-preservationglp-1clinical-trialdrug-development