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Zola-Cel CAR T-Cell Therapy Shows Promising Initial Results in Multiple Sclerosis
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Fusion42 · 26 October 2026 · Fusion42 review
Early results from the Breakfree-2 phase 1 trial indicate that zola-cel, a CD19-directed CAR T-cell therapy, shows promising safety and efficacy in treating highly active relapsing and progressive multiple sclerosis, with sustained clinical stability and disease improvement at six months post-infusion.
This Wire brief sits within Fusion42's coverage of Biotech.
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You now have a new option to target B cells more deeply in MS with CAR T therapy, bypassing limits of antibodies. Expect rapid shifts in treatment approaches and clinical trials around this immune reset method.
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1 source · 26 Oct 2026
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